Bioreactors and Cultivation Systems for Cell and Tissue Culture
نویسندگان
چکیده
منابع مشابه
CFD for Characterizing Standard and Single-use Stirred Cell Culture Bioreactors
Driven by global competition and rising cost pressure in the pharmaceutical industry, over the last ten years single-use bioreactors have been increasingly used for animal cell cultivations in screening experiments, seed inoculum and seed train productions as well as in small and medium scale production processes of proteins (in particular, antibodies and vaccines). In contrast to re-usable bio...
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Bioactive compounds extracted from plants are widely used. The natural habitats for a large number of plants are rapidly destroyed leading to extinction of many valuable and even endemic species. Studies on the production of plant metabolites by callus and cell suspension cultures have been carried out on an increasing scale since the end of the 1950's. The prospect of using such culturing tech...
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Despite advances in bone tissue engineering, auto grafts from intra-oral or extra-oral donor sites are still the gold standard for treatment of large craniomaxillofacial defects. Biomaterial development, application of growth factor, and stem cells, open new gateway to bone regeneration studies, but real translation from bench to bedside have not yet happened. In this review article, a number o...
متن کاملA modular flow-chamber bioreactor concept as a tool for continuous 2D- and 3D-cell culture
Background Advanced cell culture models, especially long-term 3D systems, require bioreactors allowing for cultivation under continuous flow conditions. Such culture models are for example tissue engineered implants, 3D cultures for drug testing, in vitro models of cell growth and migration for wound healing studies, cell cultures for biomaterial testing. New challenges in drug testing and biom...
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Introduction The purpose of a seed train is the generation of an adequate number of cells for the inoculation of a production bioreactor. This is timeand cost-intensive: From volumes used for cell thawing or cell line maintenance the cell number has to be increased. The cells are usually run through many cultivation systems which become larger with each passage (e.g. T-flasks, roller bottles or...
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